Risk factors of keloids in Syrians: review and research study

1- A review study gives a comprehensive view of keloid formation: Keloid is a benign fibrous growth, which presents in scar tissue of predisposed individuals. It is a result of irregular wound healing, but the exact mechanism is unknown. However, several factors may play a role in keloid formation and consequentially in predicting keloid’s behavior in response to treatment and prognosis. Keloids appear as firm, mildly tender, bosselated tumors with a shiny surface. The main differential diagnosis is hypertrophic scar, which not only a clinical challenge, but also histological challenge. No single therapeutic modality is best for all keloid, so prevention is the first rule in keloid therapy......2- A research study investigated risk factors of keloids in Syrians: There are no studies of keloids in Syria, and limited studies on Caucasians. This is the main objective of this research study. We have studied the associations among the age of onset, sex, causes of scarring, blood groups, anatomical sites, family history and number of injured anatomical sites to demonstrate some of risk factors of keloids in Syrians (Caucasians). we found out new risk factors, and confirmed others.