LAP Lambert Academic Publishing ( 2017-01-13 )
€ 35,90
Psoriasis vulgaris is a common, chronic, relapsing skin disease characterized by predominant involvement of skin, nails and joints. Recent advances in its pathophysiology have shifted the notion of psoriasis from that of a 'disease of the skin' to a 'T-cell mediated systemic disease'. Metformin acts as a modulator of the immune system, in psoriatic patients and has a remarkable effect on the early stages of psoriasis. The activation of PPAR-γ by pioglitazone results in a reduction of the formation of the proinflammatory cytokines, and the inflammatory cells infiltration. These findings support the potential use of PPAR-γ ligands as therapeutic agents in the therapy of conditions associated with autoimmune disease.
Book Details: |
|
ISBN-13: |
978-3-330-02945-3 |
ISBN-10: |
3330029455 |
EAN: |
9783330029453 |
Book language: |
English |
By (author) : |
Rehab Elgharabawy |
Number of pages: |
56 |
Published on: |
2017-01-13 |
Category: |
Clinical disciplines |