Ebola Hemorrhagic Fever: Understanding of Pathogenesis and Management

The Ebola virus, being primarily pathogenic for human and non-human primates is at present one of the most terrifying pathogens internationally. Almost five species of Ebola virus have been identified following various outbreaks in Africa and Europe. Spread of virus from primary infection site occurs through immune components i.e. monocytes, macrophages and dendritic cells, which results in end organ failure and hemorrhage. Currently, there are no approved treatment options available. Present protocol for the management relies upon early diagnosis, isolation measures and symptomatic treatment of patients.