Pharmacological Correction of the Retinal Pathology in Experiment

The book describes the ways of modeling and correcting the retinal pathology, namely hypertensive neuroretinopathy and retinal ischemia, in experiment on Wistar rats. Ethical principles of handling laboratory animals in all experiments are observed in accordance with the «European Convention for the Protection of Vertebral Animals Used for Experimental and Other Scientific Purposes. CETS No. 123». As retinoprotectors, a new dimethylaminoethanol derivative, recombinant erythropoietin in suberythrostimulating dose, sildenafil and minoxidil were studied. The results of the studies are confirmed by instrumental methods of analysis and histological studies. The novelty of the studies is confirmed by the presence of a patent of the Russian Federation for invention (RU 2539629) and applications for patents.