Potential Biological Activities of Eleusine indica

Eleusine indica L. Gaertn also known as wire grass belonging to family poaceae. The present investigation was carried out to isolate, purify and characterize active constituents from the whole plant of Eleusine indica L. Gaertn. The various phytochemical tests were performed for alkaloids, glycosides, phenolic, flavonoids etc. TLC and HPTLC were done for isolation of compounds. The isolated compounds were further characterized by FTIR, Ultraviolet spectroscopy, GC-MS and NMR. The anti-hypertensive and diuretic activity was evaluated by using in-vivo models. Anti-urolithiatic activity was evaluated by using in-vitro model. The ethanolic extract of Eleusine indica L. Gaertn significantly inhibited the hypertension case of diuretic activity ethanol extract increase the total urine volume and total content of sodium, potassium and chloride ions in urine. In the case of antiurolithiatic activity ethanolic extract significantly dissolved the calcium oxalate stones. Thus ethanolic extract of whole plant of Eleusine indica L. Gaertn have significant anti-hypertensive, diuretic and anti-urolithiatic activity.