Synthesis and Biological Evaluation of Cu, Ni, Mn and Zn Complexes

New Schiff base complexes of Copper, Nickel, Manganese and Zinc derived from Azithromycin with salicylaldehyde have been synthesized. Complexes was synthesized and physico-chemically characterized by solubility testing, melting point and FTIR. The synthesized metal complex was evaluated for antibacterial activity against the multidrug resistant pathogens, such as Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus and antifungal activity in opposition to Aspergillus niger and Aspergillus flavus. The metal complex showed the significant antibacterial and antifungal activity in comparison with free ligand.