Basics of Chalcone and related Novel Synthesis

Kinetic studies have been reported for base catalyzed formation of chalcone and its derivatives. During the present century, chalcones and their derivatives have been observed to be much use. Thus, some chalcones exhibit therapeutic properties e.g. anticular activity, hypotensive activity etc. Antibiotic activity has been shown by some chalcones due to presence of an enone function. It has been observed that the bacteriostatic or bactericidal property gets increased with the introduction of a substituent like a nitro or bromo group at the position or a bromo or hydroxyl group at the position.