Antimicrobial Metabolite from Aureobasidium pullulans

Antimicrobial substances are mainly produced by bacteria and lower fungi, and have great roles in the treatment of most infectious diseases. Propose of this book is production of antimicrobial metabolites from indigenous stains of A. pullulans by development of a cultural medium using factorial design. The antimicrobial activity of A. pullulans seemed to be associated with primary metabolite rather than secondary metabolites. However, this conclusion should be taken with caution because both secondary metabolites as well as antibiotics are heterogeneous group and our knowledge regarding the exact definition and secondary metabolite / antibiotics are far from perfection.