Formulation and Evaluation of Rabeprazole sodium microspheres

Microspheres constitute an important part of particulate drug delivery systems by virtue of their small size and efficient carrier capacity. Microspheres are the carrier linked drug delivery system in which particle size is ranges from 1-1000 µm range in diameter having a core of drug and entirely outer layers of polymer as coating material. Microsphere drug administration offers a number of advantages in therapeutics ,where the controlled release of drug delivery as well as the predictable and reproducible drug release kinetics are important feature of them.The main aim and objective of the present study was to investigate the possibility of obtaining a prolonged relatively constant effective level of Rabeprazole sodium using sodium CMC as polymer.