LAP Lambert Academic Publishing ( 22.04.2012 )
€ 49,00
A series of novel phthalimide derivatives (SV 1-8) have been synthesized and evaluated for antimicrobial activity. The target compounds were prepared by fusion of glycine with phthalic anhydride at 150-155 ºC to afford 2-(1, 3- dioxoisoindolin-2-yl) acetic acid. The compound 2-(1, 3-dioxoisoindolin-2-yl) acetic acid was treated with thionyl chloride in chloroform to afford 2-(1, 3-dioxoisoindolin-2-yl) acetyl chloride which was further treated with substituted phenols in presence of anhydrous potassium carbonate in dry acetone yielded the final compounds (SV1-8). The structures of the target compounds were characterized on the basis of their m.p., TLC, IR and 1H-NMR data. All the target compounds were evaluated for antibacterial and antifungal activity.
Kitap detayları: |
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ISBN-13: |
978-3-8454-1838-4 |
ISBN-10: |
3845418389 |
EAN: |
9783845418384 |
Kitabın dili: |
English |
Yazar: |
Shakir Saleem |
Sayfa sayısı: |
108 |
Yayın tarihi: |
22.04.2012 |
Kategori: |
Monografiler |