Synthesis and Antimicrobial Screening of Pyrazole Compounds

The rising prevalence of multi-drug resistant Gram-positive, Gram-negative bacteria and fungi continues to provide momentum for the search and development of novel antimicrobial agents active against these pathogens. In the light of interesting biological activities associated with pyrazole based pyrazoline and pyridine derivatives. In search of new bio-active molecules, the development of hybrid molecules through the combination of three pharmacophores in one frame may lead to compounds with interesting biological results.