Histochemical and Biochemical Changes in Skin Aging

The skin is one of the largest and widest organ of the body, it consists of two main parts, epidermis and dermis. Aging has many effects on a person’s skin, from wrinkles and sags to increased risk of certain skin conditions, such as skin cancer. As people age, their skin begins to change due to environmental factors, genetic makeup, nutrition and other factors. This study is an attempt to understand some of the changes that happen in skin aging including changes in the general morphological and architectural arrangement, cellularity, epidermal thickening, and basement membrane changes and demonstration of melanocytes and the biochemical profile including serum malondialdehyde level and blood superoxide dismutase level.