Modulation of growth factors in experimental cardiomyopathy

Modulation of growth factors in experimental cardiomyopathy

Tachcardia-indused diated cardiomyopathy and ischemic cardiomyopathy

LAP Lambert Academic Publishing ( 15.09.2010 )

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Different types of cardiomyopathies are associated with variable hypertrophic response. A number of growth factors are thought to play a role in pathologic cardiac remodeling. We compared the modulation of the TGF- superfamily and IGF-1 signaling pathways and their target genes, the cell cycle regulatory proteins in tachycardia-induced dilated cardiomyopathy, a model with no detectable hypertrophy and in ischemic cardiomyopathy, a model with a marked hypertrophic reaction. Tachycardiomyopathy was characterized by chambers dilation with no identifiable hypertrophy. Ischemic cardiomyopathy was characterized by eccentric hypertrophy.

Kitap detayları:

ISBN-13:

978-3-8383-3261-1

ISBN-10:

383833261X

EAN:

9783838332611

Kitabın dili:

English

Yazar:

Maryam Mahmoudabady

Sayfa sayısı:

124

Yayın tarihi:

15.09.2010

Kategori:

Klinik disiplinler