LAP Lambert Academic Publishing ( 2017-08-16 )
€ 35,90
Cervical cancer is among the cancers affecting women worldwide with high mortality rate. Human papillomavirus (HPV) is the most risk factor for cervical cancer infection, almost 99% of cervical cancers worldwide, apart from other factors. HPV succeeded in causing cervical cancer through up-regulation of cyclooxygenase (COX). COX is of two types, COX-1 and COX-2 and is present in small amount in every cell, and it participated in regulation in cervical cancer neoplasia. However, it is over-expressed in considerable amount in cervical cancers. Pharmacological inhibition of COX-1 and 2 decreases tumour formation, and makes it a very important tool for therapeutic and chemoprevention of cervical cancer. Non-steroidal anti-inflammatory drugs that is Acetylsalicylic acid and Salicylic acid are found to be inhibitor of cyclooxygenase enzymes, these drugs has been in application for anti-oxidative, anti-microbial as well as anti-inflammatory and could be applied as anti-tumour drugs in many cancer cell lines, there is also possibility that Acetylsalicylic acid and Salicylic acid inhibits angiogenesis by inhibition of COX in cervical cancer.
Book Details: |
|
ISBN-13: |
978-3-659-76267-3 |
ISBN-10: |
3659762679 |
EAN: |
9783659762673 |
Book language: |
English |
By (author) : |
Ibrahim Mohammed |
Number of pages: |
64 |
Published on: |
2017-08-16 |
Category: |
Clinical disciplines |